Evolutionary genomics & gene regulation.

Joshua Rest’s lab @ Ecology and Evolution @ Stony Brook University. We use computation, experiments, and natural history to study the evolution of biological systems.

News

New publication: Horizontal gene transfer and fusion spread carotenogenesis among diverse heterotrophic protists

The accepted manuscript features the dissertation work of Mariana Rius and is a collaboration w/ Jackie Collier and John Archibald’s lab was recently made available here at the Genome Biology and Evolution website.

Last updated on Feb 24, 2023 1 min read

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Projects

Phylogenetic Gene Expression Meta-Analysis

Does the expression of vertebrate genes evolve under purifying selection? Resolving the regulatory innovation paradox.

Joshua Rest, Injun-Choi, Keffy Kehrli, Whitney Wong

Cell to Cell Expression Variation

Does the distribution of protein expression levels vary and evolve? Why?

Nina Gu, Jordan Chee, Joshua Rest, Kash Bandaralage

Functional Genomics of Labyrinthulomycetes.

Developing tools to investigate genes involved in ecologically and evolutionarily interesting labyrinthulomycete traits, including carotenoid biosynthesis and the production of the ectoplasmic network.

Mariana Rius, Joshua Rest, Michael Horowitz, Anbarasu Karthikaichamy

Project Video