Evolutionary genomics & gene regulation.

Joshua Rest’s lab @ Ecology and Evolution @ Stony Brook University. We use computation, experiments, and natural history to study the evolution of biological systems.

News

The Unraveling of a Protist Genome Could Unlock the Mystery of Marine Viruses

Findings published in Current Biology set stage to better understand the �invisible� ocean ecosystem and its importance. Read the full press release.
Last updated on Oct 31, 2023 1 min read
See all posts

Projects

Phylogenetic Gene Expression Meta-Analysis

Does the expression of vertebrate genes evolve under purifying selection? Resolving the regulatory innovation paradox.

Cell to Cell Expression Variation

Does the distribution of protein expression levels vary and evolve? Why?

Functional Genomics of Labyrinthulomycetes.

Developing tools to investigate genes involved in ecologically and evolutionarily interesting labyrinthulomycete traits, including carotenoid biosynthesis and the production of the ectoplasmic network.
Project Video

Meet the Team

Principal Investigator

Avatar

Joshua Rest

Associate Professor

Grad Students

Avatar

Alex Gil Gomez

Undergraduate Researchers

Avatar

Natalie Sokolow

Avatar

Pasquale Matera

Collaborating Alumni

Avatar

Kash Bandaralage

Avatar

Mariana Rius

Avatar

Priya Aggarwal

Alumni

Avatar

Anbarasu Karthikaichamy

Avatar

Jordan Chee

Avatar

Keffy Kehrli

Avatar

Michael Horowitz

Avatar

Niamh O'Hara

Avatar

Nina Gu

Avatar

Whitney Wong

Publications

Horizontal gene transfer and fusion spread carotenogenesis among diverse heterotrophic protists

Thraustochytrids (phylum: Labyrinthulomycota) are non-photosynthetic marine protists. Some thraustochytrids have crtIBY, a …
Mariana Rius, Joshua S Rest, Gina V Filloramo, Anna M G Novák Vanclová, John M Archibald, Jackie L Collier
PDF DOI

The protist Aurantiochytrium has universal subtelomeric rDNAs and is a host for mirusviruses

Summary Viruses are the most abundant biological entities in the world’s oceans, where they play important ecological and …
Jackie L. Collier, Joshua S. Rest, Lucie Gallot-Lavallée, Erik Lavington, Alan Kuo, Jerry Jenkins, Chris Plott, Jasmyn Pangilinan, Chris Daum, Igor V. Grigoriev, Gina V. Filloramo, Anna M. G. Novák Vanclová, John M. Archibald
PDF DOI

Evolution of pathogen response genes associated with increased disease susceptibility during adaptation to an extreme drought in a Brassica rapa plant population

Niamh B O’Hara, Steven J Franks, Nolan C Kane, Silas Tittes, Joshua S Rest
PDF

Rapid evolutionary changes in gene expression in response to climate fluctuations

Elena Hamann, Christopher S Pauli, Zoé Joly-Lopez, Simon C Groen, Joshua S Rest, Nolan C Kane, Michael D Purugganan, Steven J Franks
PDF

Nicotine Stimulates Peristalsis in N. Vectensis: From Behavior to Nicotinic Receptor Genes

Joanne Figueiredo, Joshua Rest, Sarah Adamo, Rebecca Grella, James Dilger
See all publications

Contact