Evolutionary genomics & gene regulation.

Joshua Rest’s lab @ Ecology and Evolution @ Stony Brook University. We use computation, experiments, and natural history to study the evolution of biological systems.

News

Preprint: Nicotine Stimulates Peristalsis in N. vectensis: From Behavior to Nicotinic Receptor Genes

View the preprint at research square.
Last updated on Feb 19, 2021 1 min read

Preprint: Evolution of pathogen response genes associated with increased disease susceptibility during adaptation to an extreme drought in a Brassica rapa plant population

View the preprint at research square.
Joshua Rest, Niamh B O'Hara
Last updated on Feb 17, 2021 1 min read

Alex wins Slobodkin Award

Alex Gil Gomez was awarded a Slobodkin Award at our annual Ecology and Evolution retreat. He will use the award to fund his upcoming publications and attendance at scientific conferences.
Last updated on Feb 10, 2021 1 min read

New grant to study bothrosomes!

Along with PI Jackie Collier and co-PI Dave Matus, we have recieved a seed grant from the School of Atmospheric and Marine Sciences to study “A unique organelle at the interface of the carbon cycle and marine food webs”.
Last updated on Feb 17, 2021 1 min read

Keffy Kehrli describes his thesis in three minutes.

Graduate student Keffy Kehrli has won 3rd place in SBU’s Three Minute Thesis Virtual Competition.
Last updated on May 4, 2020 1 min read
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Projects

Phylogenetic Gene Expression Meta-Analysis

Does the expression of vertebrate genes evolve under purifying selection? Resolving the regulatory innovation paradox.

Cell to Cell Expression Variation

Does the distribution of protein expression levels vary and evolve? Why?

Functional Genomics of Labyrinthulomycetes.

Developing tools to investigate genes involved in ecologically and evolutionarily interesting labyrinthulomycete traits, including carotenoid biosynthesis and the production of the ectoplasmic network.
Project Video

Meet the Team

Principal Investigator

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Joshua Rest

Associate Professor

Post-docs

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Anbarasu Karthikaichamy

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Mariana Rius

Grad Students

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Alex Gil Gomez

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Keffy Kehrli

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Michael Horowitz

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Wensheng Liu

Undergraduate Researchers

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Injun Choi

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Jordan Chee

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Nina Gu

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Priya Aggarwal

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Whitney Wong

Alumni

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Kash Bandaralage

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Niamh O'Hara

Publications

Nicotine Stimulates Peristalsis in N. Vectensis: From Behavior to Nicotinic Receptor Genes

Joanne Figueiredo, Joshua Rest, Sarah Adamo, Rebecca Grella, James Dilger

Rapid evolutionary changes in gene expression in response to climate fluctuations

Elena Hamann, Christopher S Pauli, Zoé Joly-Lopez, Simon C Groen, Joshua S Rest, Nolan C Kane, Michael D Purugganan, Steven J Franks
PDF

Evolution of pathogen response genes associated with increased disease susceptibility during adaptation to an extreme drought in a Brassica rapa plant population

Niamh B O’Hara, Steven J Franks, Nolan C Kane, Silas Tittes, Joshua S Rest
PDF

Genetic tool development in marine protists: emerging model organisms for experimental cell biology

Drahomı́ra Faktorová, R Ellen R Nisbet, José A Fernández Robledo, Elena Casacuberta, Lisa Sudek, Andrew E Allen, Manuel Ares, Cristina Aresté, Cecilia Balestreri, Adrian C Barbrook, Joshua S Rest, Mariana Rius, others
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Widespread ancient whole-genome duplications in Malpighiales coincide with Eocene global climatic upheaval

Liming Cai, Zhenxiang Xi, André M Amorim, Manickam Sugumaran, Joshua Rest, Liang Liu, Charles C Davis
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