Evolutionary genomics & gene regulation.

Joshua Rest’s lab @ Ecology and Evolution @ Stony Brook University. We use computation, experiments, and natural history to study the evolution of biological systems.

News

New publication: Horizontal gene transfer and fusion spread carotenogenesis among diverse heterotrophic protists

The accepted manuscript features the dissertation work of Mariana Rius and is a collaboration w/ Jackie Collier and John Archibald’s lab was recently made available here at the Genome Biology and Evolution website.

Projects

Phylogenetic Gene Expression Meta-Analysis

Does the expression of vertebrate genes evolve under purifying selection? Resolving the regulatory innovation paradox.

Cell to Cell Expression Variation

Does the distribution of protein expression levels vary and evolve? Why?

Functional Genomics of Labyrinthulomycetes.

Developing tools to investigate genes involved in ecologically and evolutionarily interesting labyrinthulomycete traits, including carotenoid biosynthesis and the production of the ectoplasmic network.

Publications

Horizontal gene transfer and fusion spread carotenogenesis among diverse heterotrophic protists

Thraustochytrids (phylum: Labyrinthulomycota) are non-photosynthetic marine protists. Some thraustochytrids have crtIBY, a …

Rapid evolutionary changes in gene expression in response to climate fluctuations

Nicotine Stimulates Peristalsis in N. Vectensis: From Behavior to Nicotinic Receptor Genes

Genetic tool development in marine protists: emerging model organisms for experimental cell biology

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